Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ACSS2 | Q9NR19 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531498 | 0.95 | USP2 (0.41) | KMT2AACSS2RAB9AUSP2RORC | |
| SCHEMBL11534182 | 0.90 | KMT2A (0.48) | KMT2AACSS2MEN1RORCAHR | |
| SCHEMBL11531933 | 0.84 | KMT2A (0.45) | KMT2AACSS2RAB9AAHR | |
| SCHEMBL11533903 | 0.84 | AHR (0.43) | KMT2AACSS2AHR | |
| SCHEMBL11536188 | 0.82 | CYP19A1 (0.41) | KMT2A | |
| SCHEMBL11534280 | 0.81 | KMT2A (0.47) | KMT2AACSS2MEN1ATM | |
| SCHEMBL6544989 | 0.81 | KMT2A (0.50) | KMT2AACSS2RAB9AUSP2MEN1 | |
| SCHEMBL11533532 | 0.81 | RAB9A (0.48) | KMT2ARAB9AUSP2MEN1 | |
| SCHEMBL11540363 | 0.80 | CYP19A1 (0.50) | RAB9AUSP2RORC | |
| SCHEMBL11534499 | 0.78 | KCNH2 (0.40) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |