Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17083367 | 0.81 | ALDH1A1 (0.48) | LMNASMN1; SMN2ALDH1A1MCOLN3KMT2A | |
| SCHEMBL11527671 | 0.80 | ALDH1A1 (0.52) | LMNASMN1; SMN2ALDH1A1MCOLN3KMT2A | |
| SCHEMBL11530711 | 0.79 | ALDH1A1 (0.79) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL11661328 | 0.78 | ALDH1A1 (0.53) | LMNASMN1; SMN2ALDH1A1MCOLN3KMT2A | |
| SCHEMBL11529702 | 0.78 | ALDH1A1 (0.62) | LMNASMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL20657481 | 0.77 | TP53 (0.67) | LMNASMN1; SMN2ALDH1A1MCOLN3KMT2A | |
| SCHEMBL11526649 | 0.76 | SMN1; SMN2 (0.67) | LMNASMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL11532541 | 0.76 | ALDH1A1 (0.67) | LMNASMN1; SMN2ALDH1A1MAPTALOX12 | |
| SCHEMBL11527987 | 0.76 | ALDH1A1 (0.67) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL11525733 | 0.76 | ALDH1A1 (0.60) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168151-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-09-18 | — | — | US | disclosed |
| US-4153443-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4123251-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |