Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | USP2 | O75604 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529782 | 0.83 | MAPT (0.47) | KMT2AMAPTTHRBCYP1A2CYP3A4 | |
| SCHEMBL11538824 | 0.82 | MAOB (0.46) | CYP1A2CYP3A4CYP2C19USP2CYP2C9 | |
| SCHEMBL10921216 | 0.71 | CYP1A2 (0.43) | KMT2ATHRBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14117318 | 0.66 | KDM4E (0.56) | TSHRALDH1A1MAPK1FFAR1POLB | |
| SCHEMBL21116575 | 0.66 | IDO1 (0.50) | ALDH1A1FFAR1 | |
| SCHEMBL7776888 | 0.65 | FFAR1 (0.44) | ALDH1A1CMA1FFAR1 | |
| SCHEMBL1607526 | 0.65 | MAOB (0.48) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL2438260 | 0.65 | MAOB (0.43) | TSHRALDH1A1FFAR1 | |
| SCHEMBL1135279 | 0.65 | FYN (0.56) | TSHRALDH1A1MAPK1FFAR1 | |
| SCHEMBL6489910 | 0.65 | MAOB (0.54) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145546-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-03-20 | — | — | US | disclosed |