Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.44 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.44 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.43 |
| ▸ | USP2 | O75604 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533616 | 0.83 | KMT2A (0.43) | MAPTTHRBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11538824 | 0.77 | MAOB (0.46) | CYP1A2CYP3A4CYP2C19CYP2C9USP2 | |
| SCHEMBL11531524 | 0.76 | KMT2A (0.44) | MAPTTHRBSLC2A1SLC2A4SLC2A8 | |
| SCHEMBL10921216 | 0.71 | CYP1A2 (0.43) | THRBCYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL24041762 | 0.70 | BCHE (0.50) | SLC2A1SLC2A4SLC2A8 | |
| SCHEMBL15015882 | 0.70 | ATM (0.47) | MAPTCYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL11459041 | 0.69 | PLA2G7 (0.51) | SLC2A1KMT2ATP53MEN1 | |
| SCHEMBL11531515 | 0.68 | MAPT (0.52) | MAPTSLC2A1SLC2A4SLC2A8LMNA | |
| SCHEMBL24041787 | 0.67 | BCHE (0.45) | SLC2A1SLC2A4SLC2A8ALOX15 | |
| SCHEMBL24041759 | 0.67 | SLC2A1 (0.50) | SLC2A1SLC2A4SLC2A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145546-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-03-20 | — | — | US | disclosed |