Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568430 | 1.00 | DNM1 (0.52) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL8467889 | 0.97 | — | — | |
| SCHEMBL2108013 | 0.89 | — | — | |
| SCHEMBL11691580 | 0.82 | DNM1 (0.50) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL11788485 | 0.82 | DNM1 (0.50) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL9627846 | 0.81 | DNM1 (0.48) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL9714692 | 0.80 | DNM1 (0.48) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL9714750 | 0.80 | DNM1 (0.48) | DNM1THRBTSHRMEN1HTT | |
| Ammonia Solution, Strong SCHEMBL8616329 | 0.80 | DNM1 (0.48) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL27462497 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169147-A | Novel transient pro-drug forms of phenylbutazone and oxyphenbutazone in compositions and methods of use | INTERX RESEARCH CORPORATION (US) | 1979-09-25 | — | — | US | disclosed |
| US-4139709-A | 1,2-Diphenyl-3,5-ditrifluoroacetyloxy-4-butyl-5-hydroxy-3-pyrazoline | INTERX RESEARCH CORPORATION (US) | 1979-02-13 | — | — | US | disclosed |
| US-4117232-A | TRANSIENT PRO-DRUG FORMS OF PHENYLBUTAZONE | INTERX RESEARCH CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4036845-A | Novel transient acyl derivatives of phenylbutazone | INTERX RESEARCH CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-3957803-A | CERTAIN TRANSIENT PRO-DRUG FORMS OF PHENYLBUTAZONE | INTERX RESEARCH CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |