Bromide

Bromide

SCHEMBL11533955

CCCCCCCCCCCC[n+]1ccn(CC)c1.[Br-]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.50
CHRM4 known ✓ P08173 1/20 0.50
CHRM5 known ✓ P08912 1/20 0.50
CHRM1 known ✓ P11229 1/20 0.50
CHRM3 known ✓ P20309 1/20 0.50
ACHE known ✓ P22303 1/20 0.50
HSP90AA1 P07900 3/20 0.50
KMT2A Q03164 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
RAD52 P43351 2/20 0.50
EGFR P00533 1/20 0.50
LMNA P02545 1/20 0.50
PLA2G1B P04054 1/20 0.50
ERBB2 P04626 1/20 0.50
LCK P06239 1/20 0.50
FYN P06241 1/20 0.50
ADRA2A P08913 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL11534240 1.00 HSP90AA1 (0.50) HSP90AA1KMT2ASMN1; SMN2RAD52EGFR
Bromide SCHEMBL6114946 1.00 HSP90AA1 (0.50) HSP90AA1KMT2ASMN1; SMN2RAD52EGFR
Bromide SCHEMBL11539668 1.00 HSP90AA1 (0.50) HSP90AA1KMT2ASMN1; SMN2RAD52EGFR
SCHEMBL409128 0.98 ABCB11 (0.48) HSP90AA1KMT2ASMN1; SMN2CHRM2ADRA2A
SCHEMBL898377 0.98 ABCB11 (0.48) HSP90AA1KMT2ASMN1; SMN2CHRM2ADRA2A
SCHEMBL5291584 0.98 ABCB11 (0.48) HSP90AA1KMT2ASMN1; SMN2CHRM2ADRA2A
SCHEMBL5287687 0.98 ABCB11 (0.48) HSP90AA1KMT2ASMN1; SMN2CHRM2ADRA2A
SCHEMBL5288768 0.98 ABCB11 (0.48) HSP90AA1KMT2ASMN1; SMN2CHRM2ADRA2A
SCHEMBL899147 0.98 ABCB11 (0.48) HSP90AA1KMT2ASMN1; SMN2CHRM2ADRA2A
SCHEMBL413382 0.98 ABCB11 (0.48) HSP90AA1KMT2ASMN1; SMN2CHRM2ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4150967-A QUATERNARY IMIDAZOLIUM COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed