Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753467 | 0.83 | KMT2A (0.43) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL11533606 | 0.82 | ALOX5 (0.48) | ALOX5KMT2AMEN1CA1CA2 | |
| SCHEMBL31435209 | 0.79 | ALOX5 (0.61) | ALOX5KMT2AMEN1CA12CA1 | |
| SCHEMBL5127532 | 0.79 | ALOX5 (0.61) | ALOX5KMT2AMEN1CA12CA1 | |
| SCHEMBL27476665 | 0.79 | ALOX5 (0.48) | ALOX5KMT2AMEN1MAPTNPC1 | |
| SCHEMBL25228565 | 0.78 | ALOX5 (0.59) | ALOX5KMT2AMEN1CA12CA1 | |
| SCHEMBL30786817 | 0.77 | — | — | |
| SCHEMBL28840933 | 0.77 | — | — | |
| SCHEMBL10558860 | 0.77 | ALOX5 (0.59) | ALOX5KMT2AMEN1MAPTPOLB | |
| SCHEMBL19745771 | 0.77 | ALOX5 (0.59) | ALOX5KMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132794-A | 10-Imidoylacridan compositions | MEAD JOHNSON & COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4115571-A | DIURETICS, SMOOTH MUSCLE RELAXANTS, ANTITHROMBOGENIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4094981-A | SMOOTH MUSCLE RELAXANT EMPLOYING 10-IMIDOYLACRIDANS | MEAD JOHNSON & COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4077959-A | DIURETICS, SMOOTH MUSCLE RELAXANTS, ANTITHROMBOGENIC | MEAD JOHNSON & COMPANY (US) | 1978-03-07 | — | — | US | disclosed |
| US-4046891-A | Smooth muscle relaxant process employing 10-imidoylphenoxazines | MEAD JOHNSON & COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-3962252-A | 10-IMIDOYLACRIDANS | MEAD JOHNSON & COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3946004-A | DIURETICS, MUSCLE RELAXANTS, ANTITHROMBOGENIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1976-03-23 | — | — | US | disclosed |