Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115308 | 0.79 | MEN1 (0.67) | MEN1KMT2ATDP1CYP19A1 | |
| SCHEMBL6202771 | 0.77 | KMT2A (0.54) | MEN1KMT2ATDP1CYP19A1HDAC8 | |
| SCHEMBL9363603 | 0.77 | MEN1 (0.45) | MEN1KMT2ATDP1SLC6A4CYP19A1 | |
| SCHEMBL10467590 | 0.75 | MEN1 (0.69) | MEN1KMT2ATDP1CYP19A1 | |
| SCHEMBL9191596 | 0.74 | MEN1 (0.59) | MEN1KMT2ATDP1CYP19A1 | |
| SCHEMBL10468609 | 0.72 | KMT2A (0.56) | MEN1KMT2ATDP1CYP19A1HDAC8 | |
| SCHEMBL11489337 | 0.72 | MEN1 (1.00) | MEN1KMT2ATDP1CYP19A1 | |
| SCHEMBL21654 | 0.72 | MEN1 (1.00) | MEN1KMT2ATDP1CYP19A1 | |
| SCHEMBL29934164 | 0.72 | MEN1 (1.00) | MEN1KMT2ATDP1CYP19A1 | |
| SCHEMBL11206165 | 0.71 | CYP19A1 (0.51) | MEN1KMT2ATDP1CYP19A1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |