Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533728 | 0.92 | CYP19A1 (0.38) | HSP90AA1CYP19A1LMNAMAPTKMT2A | |
| SCHEMBL11536075 | 0.92 | TSHR (0.38) | HSP90AA1CYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL11531851 | 0.88 | HSP90AA1 (0.35) | HSP90AA1CYP19A1LMNAMAPTMEN1 | |
| SCHEMBL11531946 | 0.84 | HSP90AA1 (0.41) | HSP90AA1CYP19A1LMNAMAPTMEN1 | |
| SCHEMBL11533864 | 0.84 | MEN1 (0.37) | HSP90AA1CYP19A1LMNAMAPTMEN1 | |
| SCHEMBL11532244 | 0.74 | CYP19A1 (0.66) | HSP90AA1CYP19A1LMNAMAPT | |
| SCHEMBL11540161 | 0.73 | MAPT (0.41) | HSP90AA1CYP19A1LMNAMAPTMEN1 | |
| SCHEMBL11533590 | 0.72 | CYP19A1 (0.51) | HSP90AA1CYP19A1LMNAMAPTCYP2D6 | |
| SCHEMBL11532322 | 0.72 | CYP19A1 (0.63) | HSP90AA1CYP19A1LMNAMAPTMEN1 | |
| SCHEMBL1563373 | 0.71 | HSP90AA1 (0.47) | HSP90AA1CYP19A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |