Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | FBP1 | P09467 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532183 | 1.00 | MAPT (0.64) | MAPTRAB9AKMT2ANPC1FBP1 | |
| SCHEMBL11790650 | 0.90 | MAOB (0.67) | MAPTRAB9AFBP1CYP3A4MAOB | |
| SCHEMBL11783249 | 0.89 | MAOB (0.65) | MAPTRAB9AKMT2ANPC1FBP1 | |
| SCHEMBL11534876 | 0.88 | MAPT (0.62) | MAPTRAB9AKMT2ANPC1CYP3A4 | |
| SCHEMBL11534879 | 0.88 | MAPT (0.62) | MAPTRAB9AKMT2ANPC1CYP3A4 | |
| SCHEMBL11786214 | 0.88 | MAOB (0.66) | MAPTRAB9AKMT2ANPC1FBP1 | |
| SCHEMBL11786129 | 0.88 | ABCB11 (0.70) | FBP1CYP3A4MAOBMAOAPPARA | |
| SCHEMBL11785149 | 0.88 | MAOB (0.66) | MAPTRAB9AKMT2ANPC1FBP1 | |
| SCHEMBL11533155 | 0.87 | MAPT (0.63) | MAPTRAB9AKMT2ANPC1CYP3A4 | |
| SCHEMBL11533157 | 0.87 | MAPT (0.63) | MAPTRAB9AKMT2ANPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163859-A | ANTILIPEMIC, FUNGICIDES, BACTERICIDES | G. D. SEARLE & CO. (US) | 1979-08-07 | — | — | US | claimed |
| US-4163859-A | ANTILIPEMIC, FUNGICIDES, BACTERICIDES | G. D. SEARLE & CO. (US) | 1979-08-07 | — | — | US | disclosed |