SCHEMBL1153474

SCHEMBL1153474

CCOC(=O)C1(O)CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.38
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
OPRM1 P35372 4/20 0.37
KDM4E B2RXH2 3/20 0.36
ATM Q13315 1/20 0.36
OPRD1 P41143 2/20 0.36
OPRK1 P41145 2/20 0.36
ALOX15 P16050 1/20 0.36
SLC22A1 O15245 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
KCNH2 Q12809 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3604706 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2APOLB
SCHEMBL1815035 0.98 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1MEN1KMT2APOLB
SCHEMBL5411525 0.93 SMN1; SMN2 (0.45) SMN1; SMN2ALDH1A1MEN1KMT2APOLB
SCHEMBL542029 0.89
Toluene SCHEMBL27547270 0.85 SMN1; SMN2 (0.51) SMN1; SMN2MEN1KMT2ALMNAOPRM1
SCHEMBL254353 0.80 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1MEN1KMT2APOLB
SCHEMBL7259964 0.80 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1MEN1KMT2APOLB
SCHEMBL9806689 0.80 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1MEN1KMT2APOLB
SCHEMBL15105971 0.79 SMN1; SMN2 (0.38) SMN1; SMN2ALDH1A1MEN1KMT2APOLB
SCHEMBL17027408 0.79 POLB (0.36) SMN1; SMN2ALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720451-A Preparation method of hydroxy pinacolone retinoic acid ester 广州优南科技有限公司 2024-03-19 CN claimed
CN-107333539-A A kind of basswood cuttage technique for purifying air 合肥同创园林科技有限公司 2017-11-10 CN claimed
CN-107258140-A A kind of seed accelerating germination method of ornamental plantation tree peony 合肥同创园林科技有限公司 2017-10-20 CN claimed
CN-107258430-A A kind of beech tree Technique on Cuttage Propagation 合肥同创园林科技有限公司 2017-10-20 CN claimed
CN-107182505-A A kind of pumila hardwood cuttage method 合肥同创园林科技有限公司 2017-09-22 CN claimed
CN-107173072-A A kind of gardens basswood propagation by grafiting technology 合肥同创园林科技有限公司 2017-09-19 CN claimed
CN-107094578-A A kind of cuttage technique for viewing and admiring shape lime tree 合肥同创园林科技有限公司 2017-08-29 CN claimed
CN-107094577-A A kind of economical ingot maple cottage method 合肥同创园林科技有限公司 2017-08-29 CN claimed
CN-107094507-A A kind of engrafting method of the gold leaf elm of beautifying city 合肥同创园林科技有限公司 2017-08-29 CN claimed
CN-1746160-A Synthesis of plant growth hormone 3-indolebutyric acid UNIV TIANJIN (CN) 2006-03-15 CN claimed
WO-2026090509-A1 SPIRO HETEROCYCLIC CDK2 INHIBITORS ARCHITECT THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-20250388565-A1 ESTROGEN RECEPTOR ALPHA DEGRADERS AND METHODS OF USE THEREOF RELAY THERAPEUTICS, INC. 2025-12-25 US disclosed
EP-4543871-A1 ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF Relay Therapeutics, Inc. (US) 2025-04-30 EP disclosed
CN-117720451-A Preparation method of hydroxy pinacolone retinoic acid ester 广州优南科技有限公司 2024-03-19 CN disclosed
WO-2024006781-A1 ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF RELAY THERAPEUTICS, INC. (US) 2024-01-04 WO disclosed
US-5994274-A Dialkyl phenyl halide-substituted keto-enols for use as herbicides and pesticides BAYER AKTIENGESELLSCHAFT (DE) 1999-11-30 US disclosed
CN-1232450-A 2-and 2, 5-substituted phenyl keto-enols BAYER AG (DE) 1999-10-20 CN disclosed
CN-1198154-A 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 1998-11-04 CN disclosed
US-5807805-A Substituted thiophene derivatives as pesticides and herbicides BAYER AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
CN-1189153-A Alkyl-dihalophenyl substituted ketoenols useful as pesticides and herbicides BAYER AG (DE) 1998-07-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388565-A1 ESTROGEN RECEPTOR ALPHA DEGRADERS AND METHODS OF USE THEREOF ESRRA, ESRRB, ESR2 SMN1; SMN2 2314/4885ALDH1A1 1679/4885MEN1 4864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.