Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604706 | 0.98 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1153474 | 0.98 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5411525 | 0.95 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL542029 | 0.91 | — | — | |
| Toluene SCHEMBL27547270 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ALMNAOPRM1 | |
| SCHEMBL7259964 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8198244 | 0.81 | TSHR (0.44) | SMN1; SMN2ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL17027408 | 0.81 | POLB (0.36) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL15105971 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1282033 | 0.81 | OPRM1 (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020936-A | A kind of preparation method of Spiromesifen and its intermediate | 山东康乔生物科技有限公司 | 2018-12-18 | — | — | CN | claimed |
| JP-5331093-A | — | — | None | — | — | JP | disclosed |
| CN-116377727-A | Laser stealth coating for fabric and application method thereof | 西京学院 | 2023-07-04 | — | — | CN | disclosed |
| WO-2020260857-A1 | HYDROXAMATE COMPOUNDS AS ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR | AdoRx Therapeutics Limited (GB) | 2020-12-30 | — | — | WO | disclosed |
| EP-3107916-B1 | SPIRO-OXAZOLONES | HOFFMANN LA ROCHE (CH) | 2019-03-20 | — | — | EP | disclosed |
| EP-3107916-B1 | SPIRO-OXAZOLONES | HOFFMANN LA ROCHE (CH) | 2019-03-20 | — | — | EP | disclosed |
| CN-105793266-B | Spiro-oxazolones | 豪夫迈·罗氏有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-109020936-A | A kind of preparation method of Spiromesifen and its intermediate | 山东康乔生物科技有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-109020936-A | A kind of preparation method of Spiromesifen and its intermediate | 山东康乔生物科技有限公司 | 2018-12-18 | — | — | CN | disclosed |
| US-9828385-B2 | Spiro-oxazolones | HOFFMANN-LA ROCHE INC. (US) | 2017-11-28 | — | — | US | disclosed |
| WO-2011153865-A1 | 3-ORTHO-METHYLPHENYL-2-OXO-1-OXASPIRO[4,4]NON-3-EN-4-OL WITH BIOLOGICAL ACTIVITY, DERIVATIVES AND PREPARATION METHOD THEREOF | 湖南化工研究院 (CN) | 2011-12-15 | — | — | WO | disclosed |
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-09-01 | — | — | US | disclosed |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-7947704-B2 | 2,4,6-phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-05-24 | — | — | US | disclosed |
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
| US-6444616-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-6130225-A | Substituted p-trifluoromethylphenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |
| EP-0923562-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006706-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | disclosed |
| JP-H05331093-A | INTERMEDIATE FOR 1,25-DIHYDROXYVITAMIN D3 | TAISHO PHARMACEUT CO LTD | 1993-12-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | CYP4X1, KCNE1, KDM4E | SMN1; SMN2 4169/4885ALDH1A1 2441/4885MEN1 4843/4885 |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | CYP4X1, KCNE1, KDM4E | SMN1; SMN2 4169/4885ALDH1A1 2441/4885MEN1 4843/4885 |
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | CYP4X1, KDM4E, KCNE1 | SMN1; SMN2 4082/4885ALDH1A1 2129/4885MEN1 4856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.