Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536593 | 0.87 | SRD5A2 (0.50) | KMT2AHPGDMAPTSRD5A2ALDH1A1 | |
| SCHEMBL11532430 | 0.85 | KMT2A (0.46) | KMT2AHPGDMAPTSRD5A2ALDH1A1 | |
| SCHEMBL11299829 | 0.80 | HPGD (1.00) | KMT2AHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL11535931 | 0.79 | NPSR1 (0.40) | KMT2AHPGDMAPTSRD5A2ALDH1A1 | |
| Methane SCHEMBL3400213 | 0.78 | HPGD (0.97) | KMT2AHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL1237189 | 0.74 | SRD5A2 (0.79) | KMT2AHPGDMAPTSRD5A2ALDH1A1 | |
| SCHEMBL11536587 | 0.74 | CYP3A4 (0.67) | KMT2AHPGDMAPTSRD5A2ALDH1A1 | |
| SCHEMBL1044812 | 0.73 | SRD5A2 (0.83) | SRD5A2CES2L3MBTL1LMNAVNN1 | |
| SCHEMBL7814255 | 0.73 | KMT2A (0.73) | KMT2AHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL8726553 | 0.72 | KMT2A (0.82) | KMT2AHPGDMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159986-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | ROUSSEL UCLAF (FR) | 1979-07-03 | — | — | US | claimed |
| US-4159986-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | ROUSSEL UCLAF (FR) | 1979-07-03 | — | — | US | disclosed |