Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533225 | 0.88 | GAA (0.44) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11533230 | 0.88 | GAA (0.44) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11531807 | 0.87 | GAA (0.41) | GAATSHRCHRM2CHRM4CHRM1 | |
| Benzil SCHEMBL15008957 | 0.86 | CYP2D6 (0.37) | GAATSHRKMT2A | |
| SCHEMBL11534640 | 0.86 | GAA (0.41) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11532899 | 0.86 | GAA (0.41) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11533829 | 0.86 | TSHR (0.44) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11530764 | 0.86 | GAA (0.42) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11533372 | 0.84 | SCN1A (0.43) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11532289 | 0.84 | CYP3A4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |