Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535558 | 0.94 | TSHR (0.42) | KCNH2GAATSHR | |
| SCHEMBL11533448 | 0.90 | THRB (0.37) | SCN1ASCN2ASCN3AKCNH2GAA | |
| SCHEMBL11532899 | 0.89 | GAA (0.41) | KCNH2GAACHRNA7TSHRCHRM2 | |
| SCHEMBL11536074 | 0.89 | BCHE (0.39) | SCN1ASCN2ASCN3AKCNH2GAA | |
| SCHEMBL11536214 | 0.89 | ABCB1 (0.38) | SCN1ASCN2ASCN3ALMNASMN1; SMN2 | |
| SCHEMBL11622780 | 0.88 | BCHE (0.45) | SCN1ASCN2ASCN3ALMNASMN1; SMN2 | |
| SCHEMBL11534640 | 0.85 | GAA (0.41) | GAATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL11534823 | 0.84 | GAA (0.44) | KCNH2GAACHRNA7TSHRCHRM2 | |
| SCHEMBL11533858 | 0.84 | KCNH2 (0.41) | KCNH2GAATSHR | |
| SCHEMBL11530973 | 0.84 | GAA (0.40) | KCNH2GAATSHRCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | claimed |
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |