Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533629 | 0.94 | HSD17B10 (0.47) | HSD17B10NPSR1NFKB1MAPK1KDM4E | |
| SCHEMBL11534759 | 0.93 | HSD17B10 (0.46) | HSD17B10NPSR1NFKB1MAPK1KDM4E | |
| SCHEMBL11537659 | 0.93 | HSD17B10 (0.46) | HSD17B10NPSR1NFKB1MAPK1KDM4E | |
| SCHEMBL11536801 | 0.93 | HSD17B10 (0.46) | HSD17B10NPSR1NFKB1MAPK1KDM4E | |
| SCHEMBL11536585 | 0.93 | HSD17B10 (0.46) | HSD17B10NPSR1NFKB1MAPK1KDM4E | |
| SCHEMBL11537625 | 0.93 | HSD17B10 (0.46) | HSD17B10NPSR1NFKB1MAPK1KDM4E | |
| SCHEMBL14843770 | 0.88 | HSD17B10 (0.52) | HSD17B10NPSR1NFKB1MAPK1KDM4E | |
| SCHEMBL9678399 | 0.88 | HSD17B10 (0.52) | HSD17B10NPSR1NFKB1MAPK1KDM4E | |
| SCHEMBL18258589 | 0.81 | NPSR1 (0.49) | HSD17B10NPSR1MAPK1ALDH1A1TP53 | |
| SCHEMBL18258587 | 0.81 | NPSR1 (0.49) | HSD17B10NPSR1MAPK1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148998-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1979-04-10 | — | — | US | disclosed |