Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536801 | 1.00 | HSD17B10 (0.46) | HSD17B10NPSR1LMNANFKB1TSHR | |
| SCHEMBL11537659 | 1.00 | HSD17B10 (0.46) | HSD17B10NPSR1LMNANFKB1TSHR | |
| SCHEMBL11536585 | 1.00 | HSD17B10 (0.46) | HSD17B10NPSR1LMNANFKB1TSHR | |
| SCHEMBL11533629 | 0.98 | HSD17B10 (0.47) | HSD17B10NPSR1LMNANFKB1TSHR | |
| SCHEMBL11535290 | 0.93 | HSD17B10 (0.49) | HSD17B10NPSR1LMNANFKB1TSHR | |
| SCHEMBL14843770 | 0.85 | HSD17B10 (0.52) | HSD17B10NPSR1NFKB1ALDH1A1KDM4E | |
| SCHEMBL9678399 | 0.85 | HSD17B10 (0.52) | HSD17B10NPSR1NFKB1ALDH1A1KDM4E | |
| SCHEMBL3868378 | 0.82 | GPR84 (0.48) | HSD17B10NPSR1FFAR4FFAR1MAPT | |
| SCHEMBL18258631 | 0.82 | GPR84 (0.48) | HSD17B10NPSR1FFAR4FFAR1MAPT | |
| SCHEMBL5524539 | 0.80 | NPSR1 (0.47) | HSD17B10NPSR1FFAR1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148998-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1979-04-10 | — | — | US | disclosed |