Ethylene Glycol

Ethylene Glycol

SCHEMBL11535314

O=C(O)CCc1ccccn1.OCCO

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.57
CYP1A2 P05177 2/20 0.57
CYP2C19 P33261 1/20 0.57
ALDH1A1 P00352 1/20 0.51
FFAR1 O14842 2/20 0.50
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PTPRA P18433 1/20 0.49
HRH1 P35367 1/20 0.48
KEAP1 Q14145 1/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 1/20 0.47
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL11532139 1.00 SMN1; SMN2 (0.57) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
SCHEMBL29499090 0.94 SMN1; SMN2 (0.62) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
SCHEMBL333243 0.94 SMN1; SMN2 (0.62) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
1,4-Butanediol SCHEMBL11531292 0.93 SMN1; SMN2 (0.58) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
Hydrochloric Acid SCHEMBL4174816 0.93 SMN1; SMN2 (0.60) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
Hydrochloric Acid SCHEMBL28672925 0.93 SMN1; SMN2 (0.60) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
Sulfuric Acid SCHEMBL933256 0.88 SMN1; SMN2 (0.55) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
SCHEMBL3673389 0.84 SMN1; SMN2 (0.73) SMN1; SMN2CYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL6687222 0.84 SMN1; SMN2 (0.73) SMN1; SMN2CYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL2302450 0.82 SMN1; SMN2 (0.66) SMN1; SMN2CYP1A2CYP2C19ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4153795-A Cobalt pyridyl catalysts for hydroformylation DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1979-05-08 US disclosed