SCHEMBL29499090

SCHEMBL29499090

O=C(O)CCc1ccccn1

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.62
CYP1A2 P05177 3/20 0.62
CYP2C19 P33261 1/20 0.62
ALDH1A1 P00352 1/20 0.56
FFAR1 O14842 2/20 0.54
HRH1 P35367 1/20 0.53
PTPRA P18433 1/20 0.53
TDP1 Q9NUW8 2/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
KEAP1 Q14145 1/20 0.52
LMNA P02545 1/20 0.49
CYP3A4 P08684 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333243 1.00 SMN1; SMN2 (0.62) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
Hydrochloric Acid SCHEMBL28672925 0.98 SMN1; SMN2 (0.60) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
Hydrochloric Acid SCHEMBL4174816 0.98 SMN1; SMN2 (0.60) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
Ethylene Glycol SCHEMBL11535314 0.94 SMN1; SMN2 (0.57) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
Ethylene Glycol SCHEMBL11532139 0.94 SMN1; SMN2 (0.57) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
Sulfuric Acid SCHEMBL933256 0.93 SMN1; SMN2 (0.55) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
1,4-Butanediol SCHEMBL11531292 0.91 SMN1; SMN2 (0.58) SMN1; SMN2CYP1A2CYP2C19ALDH1A1FFAR1
SCHEMBL6687222 0.89 SMN1; SMN2 (0.73) SMN1; SMN2CYP1A2CYP2C19ALDH1A1HRH1
SCHEMBL3673389 0.89 SMN1; SMN2 (0.73) SMN1; SMN2CYP1A2CYP2C19ALDH1A1HRH1
SCHEMBL2302450 0.87 SMN1; SMN2 (0.66) SMN1; SMN2CYP1A2CYP2C19ALDH1A1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019341-A Nitrile compound and preparation method and application thereof 苏州大学 2024-11-26 CN claimed
CN-109863146-B Biaryl compounds as immunomodulators 百时美施贵宝公司 2023-02-28 CN claimed
CN-111699176-B Quinazolinones as PARP14 inhibitors 里邦医疗公司 2025-02-14 CN disclosed
CN-115151544-B Beta-lactamase inhibitor and preparation thereof 宁夏农林科学院 2024-08-16 CN disclosed
CN-110312730-B Cytotoxins and conjugates, uses thereof and methods of preparation 四川科伦博泰生物医药股份有限公司 2024-06-18 CN disclosed
CN-117088744-A Method for constructing fluorine-containing compound by catalyzing decarboxylation of alkyl carboxylic acid by ketone compound 中山大学 2023-11-21 CN disclosed
CN-116568682-A Novel compounds for the treatment of angiotensin II related diseases 维科尔药物公司 2023-08-08 CN disclosed
EP-4146650-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION Ningxia Academy of Agriculture and Forestry Sciences (CN) 2023-03-15 EP disclosed
CN-109863146-B Biaryl compounds as immunomodulators 百时美施贵宝公司 2023-02-28 CN disclosed
CN-115151544-A Beta-lactamase inhibitors and preparation thereof 宁夏农林科学院 2022-10-04 CN disclosed
EP-3596052-B1 CHEMICAL COMPOUNDS NODTHERA LTD (GB) 2022-07-20 EP disclosed
CN-114761082-A Azepane derivatives 日本化学药品株式会社 2022-07-15 CN disclosed
WO-2022047603-A1 BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) 2022-03-10 WO disclosed