Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | SHBG | P04278 | 1/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.67 |
| ▸ | GUSB | P08236 | 1/20 | 0.67 |
| ▸ | G6PD | P11413 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535322 | 1.00 | CYP3A4 (0.67) | CYP3A4MEN1LMNASHBGSERPINA6 | |
| SCHEMBL11534540 | 0.90 | CYP3A4 (0.65) | CYP3A4MEN1LMNASHBGSERPINA6 | |
| SCHEMBL11534533 | 0.90 | CYP3A4 (0.65) | CYP3A4MEN1LMNASHBGSERPINA6 | |
| SCHEMBL11531342 | 0.90 | CYP19A1 (0.63) | CYP3A4MEN1LMNASHBGSERPINA6 | |
| SCHEMBL11531335 | 0.90 | CYP19A1 (0.63) | CYP3A4MEN1LMNASHBGSERPINA6 | |
| SCHEMBL11597443 | 0.89 | CYP3A4 (0.62) | CYP3A4MEN1LMNASHBGSERPINA6 | |
| SCHEMBL11597447 | 0.89 | CYP3A4 (0.62) | CYP3A4MEN1LMNASHBGSERPINA6 | |
| SCHEMBL11533747 | 0.86 | CYP19A1 (0.74) | CYP3A4MEN1LMNASHBGSERPINA6 | |
| SCHEMBL11533748 | 0.86 | CYP19A1 (0.74) | CYP3A4MEN1LMNASHBGSERPINA6 | |
| SCHEMBL15387006 | 0.85 | G6PD (0.76) | CYP3A4MEN1LMNASHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139617-A | STEROIDS, ANTIDEPRESSANTS | RICHARDSON-MERRELL INC. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4071625-A | 19-Oxygenated-5α-androstanes for the enhancement of libido | RICHARDSON-MERRELL INC. (US) | 1978-01-31 | — | — | US | disclosed |