Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44801 | 0.80 | CYP2C19 (1.00) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL11537189 | 0.77 | CYP2C19 (0.68) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL4133539 | 0.77 | CYP2C19 (0.72) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL11260584 | 0.77 | CYP2C19 (0.72) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL4050426 | 0.77 | CYP2C19 (0.72) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL724648 | 0.77 | CYP2C19 (0.72) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL5935700 | 0.77 | CYP2C19 (0.72) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL11535420 | 0.76 | CYP2C19 (0.66) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9622305 | 0.75 | CYP2C19 (0.55) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL11291081 | 0.75 | CYP2C19 (0.70) | CYP2C19ALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134918-A | ENZYME INHIBITORS, ANTIBODY INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1979-01-16 | — | — | US | disclosed |