Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621828 | 0.79 | CYP2C19 (0.50) | CYP2C19SMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL5935700 | 0.76 | CYP2C19 (0.72) | CYP2C19SMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL11535371 | 0.75 | CYP2C19 (0.66) | CYP2C19SMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL600051 | 0.74 | TDP1 (0.52) | CYP2C19SMN1; SMN2LMNAMDM2ALDH1A1 | |
| SCHEMBL2853917 | 0.74 | TDP1 (0.52) | CYP2C19SMN1; SMN2LMNAMDM2ALDH1A1 | |
| SCHEMBL44801 | 0.72 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL31412096 | 0.72 | TDP1 (0.50) | CYP2C19SMN1; SMN2LMNAMDM2ALDH1A1 | |
| SCHEMBL11607787 | 0.72 | TDP1 (0.50) | SMN1; SMN2LMNAMDM2ALDH1A1HPGD | |
| SCHEMBL27899184 | 0.72 | TDP1 (0.50) | CYP2C19SMN1; SMN2LMNAMDM2ALDH1A1 | |
| SCHEMBL29251170 | 0.72 | TDP1 (0.50) | CYP2C19SMN1; SMN2LMNAMDM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307358-B1 | 1,3-DIKETONES CONTAINING ETHERS OR THIOETHERS AND THEIR USE AS STABILISING AGENTS IN CHLORINATED POLYMERS | CIBA-GEIGY AG (CH) | 1992-02-12 | — | — | EP | disclosed |
| US-4992504-A | Heat resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0307358-A1 | 1,3-Diketones containing ethers or thioethers and their use as stabilising agents in chlorinated polymers | CIBA-GEIGY AG (CH) | 1989-03-15 | — | — | EP | disclosed |