Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532485 | 0.99 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11536742 | 0.99 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11534210 | 0.86 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11537408 | 0.84 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11534600 | 0.84 | TSHR (0.36) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL5808485 | 0.80 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11536086 | 0.78 | TSHR (0.38) | TSHRHPGDTHRB | |
| SCHEMBL11536000 | 0.77 | TSHR (0.38) | TSHRHPGD | |
| SCHEMBL11532059 | 0.77 | TSHR (0.38) | TSHRHPGD | |
| SCHEMBL11532661 | 0.73 | TSHR (0.37) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150234-A | WATER RESISTANT | CIBA-GEIGY CORPORATION (US) | 1979-04-17 | — | — | US | disclosed |