Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784312 | 0.84 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11054800 | 0.82 | PLA2G7 (0.36) | PLA2G7 | |
| SCHEMBL11332808 | 0.82 | ALDH1A1 (0.41) | TSHRALDH1A1PLA2G7GAARAB9A | |
| SCHEMBL11534600 | 0.80 | TSHR (0.36) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11535487 | 0.80 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11167503 | 0.79 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11536742 | 0.79 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11532485 | 0.79 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL22722643 | 0.78 | PLA2G7 (0.39) | PLA2G7RAB9A | |
| SCHEMBL10878204 | 0.78 | PLA2G7 (0.42) | TSHRALDH1A1HSD17B10PLA2G7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650845-A | SHRINKAGE-INHIBITED OPTICAL CASTINGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-17 | — | — | US | claimed |
| US-20060072445-A1 | Optical recording medium having abrasion resistance and antistatic properties | IMATION CORP. | 2006-04-06 | — | — | US | disclosed |
| WO-2006036619-A1 | OPTICAL RECORDING MEDIUM HAVING ABRASION RESISTANCE AND ANTISTATIC PROPERTIES | IMATION CORP. (US) | 2006-04-06 | — | — | WO | disclosed |
| US-4785064-A | URETHANE ACRYLATE AND POLYACRYLATE ESTER | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
| US-4650845-A | SHRINKAGE-INHIBITED OPTICAL CASTINGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| US-4125516-A | HEAT STABILIZER, ANTIOXIDANT, DISCOLORATION INHIBITON | CIBA-GEIGY CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |