Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537084 | 0.88 | CYP19A1 (0.55) | CYP19A1ALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL11532322 | 0.87 | CYP19A1 (0.63) | CYP19A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL11534015 | 0.86 | CYP19A1 (0.42) | CYP19A1ALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL11533166 | 0.83 | CYP19A1 (0.59) | CYP19A1ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL11533125 | 0.82 | CYP19A1 (0.57) | CYP19A1LMNAKMT2AHSP90AA1 | |
| SCHEMBL11531173 | 0.80 | TSHR (0.46) | CYP19A1ALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL11538658 | 0.80 | CYP19A1 (0.45) | CYP19A1ALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL11531656 | 0.80 | MEN1 (0.44) | CYP19A1ALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL11536149 | 0.79 | CYP19A1 (0.55) | CYP19A1ALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL11536619 | 0.79 | TSHR (0.45) | CYP19A1ALDH1A1KDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |