Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 2/20 | 0.31 |
| ▸ | EDNRA | P25101 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532322 | 0.87 | CYP19A1 (0.63) | CYP19A1LMNAHSP90AA1MAPTTDP1 | |
| SCHEMBL11535690 | 0.86 | CYP19A1 (0.40) | CYP19A1LMNAHSP90AA1KIF11FGFR1 | |
| SCHEMBL11533166 | 0.83 | CYP19A1 (0.59) | CYP19A1LMNAHSP90AA1KIF11MAPT | |
| SCHEMBL11533125 | 0.82 | CYP19A1 (0.57) | CYP19A1LMNAHSP90AA1 | |
| SCHEMBL11533863 | 0.80 | LMNA (0.40) | CYP19A1LMNAHSP90AA1KIF11MAPT | |
| SCHEMBL11537084 | 0.79 | CYP19A1 (0.55) | CYP19A1LMNAHSP90AA1KIF11MAPT | |
| SCHEMBL11535619 | 0.79 | CYP19A1 (0.55) | CYP19A1LMNAHSP90AA1MAPTKDM4E | |
| SCHEMBL11534144 | 0.78 | CYP19A1 (0.54) | CYP19A1LMNAHSP90AA1ALDH1A1TDP1 | |
| SCHEMBL11534672 | 0.75 | CYP19A1 (0.50) | CYP19A1LMNAHSP90AA1KIF11MAPT | |
| SCHEMBL11535433 | 0.75 | CYP19A1 (0.49) | CYP19A1LMNAHSP90AA1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |