Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500770 | 0.84 | PDK2 (0.60) | PDK2PDK4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL24740182 | 0.84 | PDK2 (0.60) | PDK2PDK4POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL14691504 | 0.79 | PDK2 (0.43) | PDK2PDK4POLBHTR5AAKR1B1 | |
| Propane SCHEMBL28210963 | 0.79 | PDK2 (0.59) | PDK2PDK4POLBHTR5AAKR1B1 | |
| Propane SCHEMBL28225298 | 0.79 | PDK2 (0.59) | PDK2PDK4POLBHTR5AAKR1B1 | |
| SCHEMBL18647358 | 0.76 | KMT2A (0.39) | PDK2ALDH1A1SMN1; SMN2NOS2HTR2A | |
| SCHEMBL29371027 | 0.75 | PDK2 (0.67) | PDK2PDK4POLBHTR5AAKR1B1 | |
| SCHEMBL31911 | 0.75 | PDK2 (0.67) | PDK2PDK4POLBHTR5AAKR1B1 | |
| SCHEMBL28706253 | 0.73 | PDK2 (0.64) | PDK2PDK4POLBHTR5AAKR1B1 | |
| SCHEMBL13827879 | 0.72 | KMT2A (0.49) | PDK2PDK4POLBHTR5ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169607-A1 | CARBAZOLE AND ACRIDINE PHOTOREDOX CATALYSTS FOR SMALL MOLECULE AND MACROMOLECULAR TRANSFORMATIONS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-06-02 | — | — | US | disclosed |
| WO-2020205765-A1 | CARBAZOLE AND ACRIDINE PHOTOREDOX CATALYSTS FOR SMALL MOLECULE AND MACROMOLECULAR TRANSFORMATIONS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2020-10-08 | — | — | WO | disclosed |
| EP-2705552-B1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-03-04 | — | — | EP | disclosed |
| US-20140061548-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | Merck Patent CmbH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-20140061548-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | Merck Patent CmbH (DE) | 2014-03-06 | — | — | US | disclosed |
| WO-2012150001-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-11-08 | — | — | WO | disclosed |
| US-4132794-A | 10-Imidoylacridan compositions | MEAD JOHNSON & COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4115571-A | DIURETICS, SMOOTH MUSCLE RELAXANTS, ANTITHROMBOGENIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4094981-A | SMOOTH MUSCLE RELAXANT EMPLOYING 10-IMIDOYLACRIDANS | MEAD JOHNSON & COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4077959-A | DIURETICS, SMOOTH MUSCLE RELAXANTS, ANTITHROMBOGENIC | MEAD JOHNSON & COMPANY (US) | 1978-03-07 | — | — | US | disclosed |
| US-4046891-A | Smooth muscle relaxant process employing 10-imidoylphenoxazines | MEAD JOHNSON & COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-3962252-A | 10-IMIDOYLACRIDANS | MEAD JOHNSON & COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3946004-A | DIURETICS, MUSCLE RELAXANTS, ANTITHROMBOGENIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169607-A1 | CARBAZOLE AND ACRIDINE PHOTOREDOX CATALYSTS FOR SMALL MOLECULE AND MACROMOLECULAR TRANSFORMATIONS | PCNA, PPOX, PARP1 | PDK2 643/4885PDK4 2453/4885POLB 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.