Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | UGCG | Q16739 | 2/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033186 | 1.00 | LMNA (0.37) | LMNATSHRSCN9ACTSLCTSB | |
| SCHEMBL11033190 | 1.00 | LMNA (0.37) | LMNATSHRSCN9ACTSLCTSB | |
| SCHEMBL11536019 | 1.00 | LMNA (0.37) | LMNATSHRSCN9ACTSLCTSB | |
| SCHEMBL11033184 | 1.00 | LMNA (0.37) | LMNATSHRSCN9ACTSLCTSB | |
| SCHEMBL11537312 | 0.85 | SCN9A (0.40) | LMNATSHRSCN9ACTSLCTSB | |
| SCHEMBL11537305 | 0.85 | SCN9A (0.40) | LMNATSHRSCN9ACTSLCTSB | |
| SCHEMBL11537309 | 0.85 | SCN9A (0.40) | LMNATSHRSCN9ACTSLCTSB | |
| SCHEMBL24007625 | 0.81 | TSHR (0.48) | LMNATSHRSCN9ACTSLCTSB | |
| SCHEMBL24815520 | 0.81 | TSHR (0.48) | LMNATSHRSCN9ACTSLCTSB | |
| SCHEMBL26024052 | 0.81 | TSHR (0.48) | LMNATSHRSCN9ACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154949-A | HYPOTENSIVE AGENTS | PFIZER INC. (US) | 1979-05-15 | — | — | US | disclosed |