Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533590 | 0.88 | CYP19A1 (0.51) | CYP19A1HSP90AA1LMNACYP3A4MAPT | |
| SCHEMBL11532598 | 0.86 | CYP19A1 (0.43) | CYP19A1HSP90AA1KIF11LMNACYP3A4 | |
| SCHEMBL11530495 | 0.84 | CYP19A1 (0.49) | CYP19A1HSP90AA1LMNACYP3A4CYP2C9 | |
| SCHEMBL11530796 | 0.81 | CYP19A1 (0.48) | CYP19A1KDM4EHSP90AA1KIF11SMN1; SMN2 | |
| SCHEMBL11531310 | 0.80 | CYP19A1 (0.49) | CYP19A1HSP90AA1KIF11SMN1; SMN2LMNA | |
| SCHEMBL11535982 | 0.79 | CYP19A1 (0.41) | CYP19A1HSP90AA1KIF11LMNACYP3A4 | |
| SCHEMBL11534672 | 0.78 | CYP19A1 (0.50) | CYP19A1KDM4EALOX15HSP90AA1KIF11 | |
| SCHEMBL21738 | 0.77 | KDM4E (0.41) | CYP19A1KDM4EALOX15HSP90AA1KIF11 | |
| SCHEMBL11534213 | 0.77 | CYP19A1 (0.47) | CYP19A1HSP90AA1LMNACYP3A4CYP1A2 | |
| SCHEMBL11532244 | 0.76 | CYP19A1 (0.66) | CYP19A1HSP90AA1LMNACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |