SCHEMBL21738

SCHEMBL21738

FC(F)(F)c1cccc(C(c2ccccc2)(c2ccccc2)n2cncn2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ALOX15 P16050 1/20 0.41
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP19A1 P11511 2/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
MAPT P10636 1/20 0.38
HSP90AA1 P07900 1/20 0.38
IDH2 P48735 1/20 0.38
NOTUM Q6P988 1/20 0.37
KIF11 P52732 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1563373 0.85 HSP90AA1 (0.47) ALOX15SMN1; SMN2RAB9ACYP19A1ALDH1A1
Ammonia Solution, Strong SCHEMBL27402390 0.84 HSP90AA1 (0.46) ALOX15SMN1; SMN2RAB9ACYP19A1ALDH1A1
SCHEMBL11534672 0.82 CYP19A1 (0.50) KDM4EALOX15HPGDSMN1; SMN2NPC1
SCHEMBL11539986 0.80 KDM4E (0.39) KDM4EALOX15HPGDSMN1; SMN2NPC1
SCHEMBL11534215 0.78 LMNA (0.40) KDM4EALOX15HPGDSMN1; SMN2RAB9A
SCHEMBL11605565 0.78 CYP19A1 (0.47) ALOX15SMN1; SMN2RAB9ACYP19A1ALDH1A1
SCHEMBL11536102 0.77 CYP19A1 (0.42) KDM4EALOX15HPGDSMN1; SMN2NPC1
SCHEMBL11533466 0.77 MAPT (0.40) KDM4EALOX15HPGDSMN1; SMN2RAB9A
SCHEMBL11531998 0.76 CES2 (0.42) HPGDSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL5290299 0.73 CYP11B1 (0.73) ALOX15SMN1; SMN2RAB9ACYP19A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4166 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
WO-2025012816-A1 FUNGICIDAL COMBINATIONS, METHODS, AND APPLICATIONS THEREOF UPL MAURITIUS LIMITED (MU) 2025-01-16 WO claimed
US-12075783-B2 Process for preparation of copper compounds UPL LTD (IN) 2024-09-03 US claimed
US-20240188569-A1 NEW YEAST STRAIN AND ITS USES FOR THE CONTROL OF PHYTOPATHOGENS AGROVENTURES LLC (US) 2024-06-13 US claimed
US-20240138408-A1 COMPOSITION COMPRISING BENZYLAMINE ACARICIDE AND USE THEREOF SHANGDONG KANGIAO BIO-TECHNOLOGY CO., LTD (CN) 2024-05-02 US claimed
EP-4331364-A2 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO Corteva Agriscience LLC (US) 2024-03-06 EP claimed
EP-4323496-A1 NEW YEAST STRAIN AND ITS USES FOR THE CONTROL OF PHYTOPATHOGENS AGROVENTURES S.R.L. (IT) 2024-02-21 EP claimed
WO-2003026421-A1 FUNGICIDAL COMPOSITIONS AND THEIR APPLICATIONS IN AGRICULTURE MONSANTO TECHNOLOGY, LLC (US) 2003-04-03 WO claimed
US-20030060371-A1 Method of improving yield and vigor of plants by treatment with diazole, triazole and strobilurin-type fungicides MONSANTO TECHNOLOGY, L.L.C. (US) 2003-03-27 US claimed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO claimed
EP-0714603-B1 Synergistic fungicidal difenzoquat compositions AMERICAN CYANAMID CO (US) 1999-09-29 EP claimed
EP-0714603-A1 Synergistic fungicidal difenzoquat compositions American Cyanamid Company (US) 1996-06-05 EP claimed
EP-0239508-A2 2-Cyano-benzimidazole derivatives, their preparation and use as fungicides, their association with other fungicides RHONE-POULENC AGROCHIMIE (FR) 1987-09-30 EP claimed
EP-0180263-A3 METHOD FOR CONTROLLING VASCULAR WITHERING DISEASES IN PLANTS, ESPECIALLY DUTCH ELM DISEASE Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO (NL) 1986-07-30 EP claimed
EP-0180263-A2 Method for controlling vascular withering diseases in plants, especially dutch elm disease Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO (NL) 1986-05-07 EP claimed
EP-0095242-A2 Fungicidal compositions and methods of treating seeds and combating fungal pest therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-30 EP claimed
US-4073901-A Metal complexes of N-trityl-azoles for combatting fungi BAYER AKTIENGESELLSCHAFT (DT) 1978-02-14 US claimed