Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
| ▸ | DRD5 | P21918 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5441998 | 0.83 | POLB (0.56) | POLBKDM4E | |
| SCHEMBL11478965 | 0.83 | POLB (0.56) | POLBKDM4EATM | |
| SCHEMBL11529719 | 0.83 | POLB (0.78) | POLBKDM4E | |
| SCHEMBL11539203 | 0.83 | MEN1 (0.66) | POLBSIGMAR1KDM4E | |
| SCHEMBL11528359 | 0.83 | POLB (0.56) | POLBHPGDDRD2DRD3DRD1 | |
| Hydrochloric Acid SCHEMBL11529713 | 0.82 | POLB (0.81) | POLBKDM4E | |
| Hydrochloric Acid SCHEMBL11534952 | 0.81 | MEN1 (0.69) | POLBSIGMAR1KDM4E | |
| SCHEMBL1448755 | 0.81 | POLB (0.54) | POLBKDM4E | |
| SCHEMBL1539950 | 0.80 | ACHE (0.50) | POLBACHEHTR1ADRD2HTR2A | |
| SCHEMBL11335407 | 0.80 | KDM4E (0.61) | HTR1ADRD2HTR2ADRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155907-A | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines | THE DOW CHEMICAL COMPANY (US) | 1979-05-22 | — | — | US | claimed |