SCHEMBL11537012

SCHEMBL11537012

C#CCCCSCCCC#C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GPR84 Q9NQS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11533019 0.90 CYP1A2 (0.39) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL1453769 0.87
SCHEMBL1017212 0.87
SCHEMBL1016734 0.83
SCHEMBL17879419 0.79 HSD17B10 (0.58) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL1454027 0.79 MAPT (0.32) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL1019773 0.79 CYP1A2 (0.32) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL1016997 0.78
SCHEMBL17879415 0.78 HSD17B10 (0.41) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL23015155 0.77 CYP1A2 (0.40) CYP1A2CYP2D6MAPTCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4150057-A ION EXCHANGING, REACTION OF BORON COMPOUND WITH DIMETHYL SULFIDE AND HYDROCHLORIC ACID THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1979-04-17 US disclosed