Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17879416 | 0.92 | MAPT (0.47) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17879418 | 0.84 | CYP1A2 (0.40) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17879419 | 0.82 | HSD17B10 (0.58) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23531362 | 0.80 | ALDH1A1 (0.47) | HSD17B10MAPTCYP2C9ALDH1A1HPGD | |
| SCHEMBL1415148 | 0.78 | — | — | |
| SCHEMBL3504701 | 0.78 | ALDH1A1 (0.56) | HSD17B10MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL11537012 | 0.78 | CYP1A2 (0.35) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8661229 | 0.76 | — | — | |
| SCHEMBL14450308 | 0.76 | HSD17B10 (0.61) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23531305 | 0.75 | ALDH1A1 (0.53) | HSD17B10MAPTALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185735-A1 | FATTY ACID ANALOGS AND THEIR USE | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185735-A1 | FATTY ACID ANALOGS AND THEIR USE | FABP4, ELOVL1, CPT1A | HSD17B10 73/4885MAPT 4417/4885CYP1A2 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.