Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | DAO | P14920 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16758990 | 0.83 | IDO1 (0.58) | IDO1PTPN5HTR2ASLC6A4KCNH2 | |
| SCHEMBL5436712 | 0.83 | SLC6A4 (0.43) | IDO1HTR2ASLC6A4KCNH2DAO | |
| SCHEMBL3188993 | 0.83 | CES2 (0.46) | IDO1PTPN5DAOCYP3A4CYP2D6 | |
| SCHEMBL30617195 | 0.83 | DAO (0.46) | IDO1PTPN5HTR2ASLC6A4KCNH2 | |
| SCHEMBL5325907 | 0.83 | IDO1 (0.58) | IDO1PTPN5HTR2ASLC6A4KCNH2 | |
| SCHEMBL1873922 | 0.83 | DAO (0.46) | IDO1HTR2ASLC6A4KCNH2DAO | |
| SCHEMBL11155123 | 0.83 | IDO1 (0.41) | IDO1PTPN5HTR2ASLC6A4KCNH2 | |
| SCHEMBL5111503 | 0.83 | DAO (0.46) | IDO1PTPN5HTR2ASLC6A4KCNH2 | |
| SCHEMBL3211500 | 0.83 | DAO (0.49) | IDO1HTR2ASLC6A4KCNH2DAO | |
| SCHEMBL3690695 | 0.81 | IDO1 (0.40) | IDO1PTPN5HTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178293-A | Isoindolinyl derivatives | ZOECON CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |