Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222515 | 0.81 | AKT1 (0.33) | AKT1 | |
| SCHEMBL11226040 | 0.80 | AKT1 (0.32) | AKT1MAPK1 | |
| SCHEMBL11227314 | 0.74 | — | — | |
| SCHEMBL11222894 | 0.73 | KLK7 (0.31) | — | |
| SCHEMBL11225165 | 0.66 | KMT2A (0.34) | — | |
| SCHEMBL11217805 | 0.66 | KMT2A (0.34) | — | |
| SCHEMBL11224044 | 0.66 | KMT2A (0.33) | — | |
| SCHEMBL11229451 | 0.64 | ALDH1A1 (0.33) | AKT1MAPK1 | |
| SCHEMBL11230716 | 0.62 | ALDH1A1 (0.34) | AKT1MAPK1 | |
| SCHEMBL11225200 | 0.60 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153612-A | 2-Benzoxepins | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | disclosed |