Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536568 | 0.84 | LMNA (0.44) | CYP19A1LMNATSHRKMT2AHSP90AA1 | |
| SCHEMBL11534485 | 0.81 | CYP19A1 (0.42) | CYP19A1LMNAKMT2AHSP90AA1MAPT | |
| SCHEMBL11533915 | 0.81 | CYP19A1 (0.37) | CYP19A1LMNATSHRHSP90AA1CYP3A4 | |
| SCHEMBL11534087 | 0.81 | CYP19A1 (0.43) | CYP19A1LMNAKMT2AHSP90AA1MAPT | |
| SCHEMBL11536335 | 0.80 | CYP19A1 (0.44) | CYP19A1LMNAKMT2AHSP90AA1CYP3A4 | |
| SCHEMBL11538629 | 0.80 | TSHR (0.41) | CYP19A1LMNATSHRKMT2AHSP90AA1 | |
| SCHEMBL11535926 | 0.79 | KMT2A (0.51) | CYP19A1LMNATSHRKMT2AHSP90AA1 | |
| SCHEMBL11530866 | 0.78 | LMNA (0.36) | CYP19A1LMNAKMT2AHSP90AA1CYP3A4 | |
| SCHEMBL11534015 | 0.77 | CYP19A1 (0.42) | CYP19A1LMNATSHRKMT2AHSP90AA1 | |
| SCHEMBL11535690 | 0.77 | CYP19A1 (0.40) | CYP19A1LMNAHSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |