Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 4/20 | 0.46 |
| ▸ | FNTB | P49356 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627075 | 0.83 | NPC1 (1.00) | NPC1TSHRPKMCA12CA1 | |
| SCHEMBL3022955 | 0.82 | NPC1 (0.59) | NPC1TSHRPKMCA12CA1 | |
| SCHEMBL2834792 | 0.79 | NPC1 (0.61) | NPC1TSHRCA12CA1CA2 | |
| SCHEMBL12972493 | 0.79 | NPC1 (0.60) | NPC1TSHRPKMCA12CA1 | |
| SCHEMBL2834927 | 0.78 | NPC1 (0.82) | NPC1TSHRCA12CA1CA2 | |
| SCHEMBL1928270 | 0.78 | NPC1 (0.54) | NPC1TSHRPKMFNTAFNTB | |
| SCHEMBL7876131 | 0.78 | SERPINE1 (0.67) | NPC1TSHRCA12CA1CA2 | |
| SCHEMBL176369 | 0.77 | CA12 (0.71) | NPC1TSHRPKMCA12CA1 | |
| SCHEMBL27828662 | 0.77 | NPC1 (0.53) | NPC1TSHRPKMCA12CA1 | |
| SCHEMBL10389513 | 0.77 | NPC1 (0.53) | NPC1TSHRLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134812-A | BLENDING WITH TETRAKIS-(METHYLENE-(3,5-DI-T-BUTYL)-4-HYDROXY-HYDROCINNAMATE)-METHANE, CROSSLINKING WITH AN ACETYLENIC COMPOUND | THE FURUKAWA ELECTRIC CO., LTD. (JP) | 1979-01-16 | — | — | US | disclosed |