SCHEMBL176369

SCHEMBL176369

C#CCOC(=O)c1ccc(C(=O)OCC#C)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.71
CA1 P00915 2/20 0.71
CA2 P00918 2/20 0.71
CA9 Q16790 2/20 0.71
CA14 Q9ULX7 2/20 0.71
NPC1 O15118 1/20 0.64
MAPT P10636 3/20 0.50
TSHR P16473 2/20 0.47
ESR1 P03372 2/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
CA7 P43166 1/20 0.45
ESR2 Q92731 1/20 0.45
LMNA P02545 4/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 1/20 0.44
MAOA P21397 1/20 0.44
CHRM1 P11229 2/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL28552075 0.94 CA1 (0.65) CA12CA1CA2CA9CA14
SCHEMBL7872582 0.92 CA12 (0.63) CA12CA1CA2CA9CA14
SCHEMBL2832918 0.92 CA1 (0.63) CA12CA1CA2CA9CA14
SCHEMBL11410746 0.90 CA12 (0.66) CA12CA1CA2CA9CA14
SCHEMBL2909577 0.90 CA12 (0.61) CA12CA1CA2CA9CA14
SCHEMBL576636 0.90 NPC1 (0.69) CA12CA1CA2CA9CA14
SCHEMBL11746611 0.89 CA12 (0.59) CA12CA1CA2CA9CA14
SCHEMBL9960375 0.87 CA1 (0.58) CA12CA1CA2CA9CA14
SCHEMBL13402894 0.87 CA12 (0.58) CA12CA1CA2CA9CA14
SCHEMBL16561571 0.87 NPC1 (0.61) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 752 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10253221-B2 Adhesive AGC Inc. (CN) 2019-04-09 US claimed
US-9815972-B2 Fluoro-rubber composition and cross-linked rubber article using same ASAHI GLASS COMPANY, LIMITED (JP) 2017-11-14 US claimed
EP-2805988-A1 METHOD FOR PRODUCING ACRYLIC RUBBER/FLUORO-RUBBER COMPOSITION, CROSSLINKED COMPOSITION, LAMINATE BODY, AND HEAT-RESISTANT AIR RUBBER HOSE Asahi Glass Company, Limited (JP) 2014-11-26 EP claimed
US-20140329096-A1 PROCESS FOR PRODUCING ACRYLIC RUBBER/FLUORINATED RUBBER COMPOSITION, CROSSLINKABLE COMPOSITION, LAMINATE AND HEAT RESISTANT AIR RUBBER HOSE ASAHI GLASS COMPANY, LIMITED (JP) 2014-11-06 US claimed
WO-2001036556-A2 FUEL BARRIER LAMINATE GOSHEN RUBBER CO., INC. (US) 2001-05-25 WO claimed
US-4251399-A AN ELASTOMER, AND AN ORGANIC PEROXIDE DAIKIN KOGYO CO., LTD. (JP) 1981-02-17 US claimed
US-4113595-A POLYOLEFIN, ACETYLENIC COMPOUND, SECONDARY AMINE JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1978-09-12 US claimed
EP-3647332-B1 FLUORINE-CONTAINING ELASTIC COPOLYMER AND PRODUCTION THEREFOR, FLUORINE-CONTAINING ELASTIC COPOLYMER COMPOSITION, AND CROSS-LINKED RUBBER ARTICLE AGC INC (JP) 2026-05-27 EP disclosed
US-20260139136-A1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR PRODUCING THE SAME DAIKIN INDUSTRIES, LTD. (JP) 2026-05-21 US disclosed
WO-2026105370-A1 SHEET, METHOD FOR PRODUCING SHEET, AND CROSSLINKED RUBBER ARTICLE AGC株式会社 2026-05-21 WO disclosed
WO-2026105786-A1 FLUORINE-CONTAINING CROSSLINKED BODY AND METHOD FOR PRODUCING SAME, AND LAMINATE AND METHOD FOR MANUFACTURING SAME AGC株式会社 2026-05-21 WO disclosed
EP-3636682-B1 FLUORINE-CONTAINING ELASTIC COPOLYMER AND PRODUCTION METHOD THEREFOR AGC INC (JP) 2026-05-06 EP disclosed
US-12583957-B2 Fluoropolymer-containing composition and molded article DAIKIN INDUSTRIES, LTD. (JP) 2026-03-24 US disclosed
US-4260698-A Co-crosslinkable blend composition comprising iodine-containing fluoroelastomer DAIKIN KOGYO CO., LTD. (JP) 1981-04-07 US disclosed
US-4251399-A AN ELASTOMER, AND AN ORGANIC PEROXIDE DAIKIN KOGYO CO., LTD. (JP) 1981-02-17 US disclosed
US-4243770-A BY POLYMERIZING VINYLIDENE FLUORIDE WITH IODOFLUOROCARBON DAIKIN KOGYO CO., LTD. (JP) 1981-01-06 US disclosed
EP-0014930-A1 Fluorine-containing polymer and composition containing same Daikin Kogyo Co., Ltd. (JP) 1980-09-03 EP disclosed
US-4134812-A BLENDING WITH TETRAKIS-(METHYLENE-(3,5-DI-T-BUTYL)-4-HYDROXY-HYDROCINNAMATE)-METHANE, CROSSLINKING WITH AN ACETYLENIC COMPOUND THE FURUKAWA ELECTRIC CO., LTD. (JP) 1979-01-16 US disclosed
US-4113595-A POLYOLEFIN, ACETYLENIC COMPOUND, SECONDARY AMINE JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1978-09-12 US disclosed
US-4062998-A Heat-resistant, resin coated electric wire characterized by three resin coatings, the outer of which is less highly cross-linked than the coating next adjacent thereto JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139136-A1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR PRODUCING THE SAME PFN1, RAD54L, FGB CA12 1994/4885CA1 858/4885CA2 2501/4885
US-12583957-B2 Fluoropolymer-containing composition and molded article AOC2, AOC1, AOC3 CA12 605/4885CA1 299/4885CA2 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.