Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | METAP1 | P53582 | 3/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12086628 | 0.87 | METAP1 (0.41) | GAAKDM4EMETAP1PPARGACHE | |
| SCHEMBL31012318 | 0.85 | METAP1 (0.42) | KDM4EMETAP1ACHECA1CA2 | |
| SCHEMBL7187309 | 0.85 | METAP1 (0.42) | KDM4EMETAP1ACHECA1CA2 | |
| SCHEMBL28440046 | 0.83 | DGAT1 (0.42) | METAP1ACHECA1CA2CA4 | |
| SCHEMBL5198058 | 0.83 | METAP1 (0.41) | KDM4EMETAP1ACHECA1CA2 | |
| SCHEMBL5200330 | 0.83 | METAP1 (0.41) | GAAKDM4EMETAP1ACHECA1 | |
| SCHEMBL11528415 | 0.82 | GAA (0.43) | GAAKDM4EMETAP1PRNPPPARG | |
| SCHEMBL5199680 | 0.80 | METAP1 (0.39) | KDM4EMETAP1ACHECA1CA2 | |
| SCHEMBL11931725 | 0.79 | METAP1 (0.38) | METAP1ACHECA1CA2CA4 | |
| SCHEMBL2351057 | 0.79 | METAP1 (0.49) | KDM4EMETAP1ACHECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |