Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537943 | 1.00 | OPRM1 (0.53) | OPRM1OPRK1OPRD1SLC6A3SLC6A2 | |
| SCHEMBL11533931 | 0.89 | SLC6A2 (0.56) | OPRM1OPRK1OPRD1SLC6A3SLC6A2 | |
| SCHEMBL11533934 | 0.89 | SLC6A2 (0.56) | OPRM1OPRK1OPRD1SLC6A3SLC6A2 | |
| SCHEMBL11193094 | 0.87 | OPRM1 (0.70) | OPRM1OPRK1OPRD1 | |
| SCHEMBL11533477 | 0.87 | OPRM1 (0.70) | OPRM1OPRK1OPRD1 | |
| SCHEMBL11193098 | 0.87 | OPRM1 (0.70) | OPRM1OPRK1OPRD1 | |
| SCHEMBL11536050 | 0.85 | SLC6A4 (0.61) | OPRM1OPRK1OPRD1SLC6A3SLC6A2 | |
| SCHEMBL11194100 | 0.85 | SLC6A4 (0.61) | OPRM1OPRK1OPRD1SLC6A3SLC6A2 | |
| SCHEMBL11194103 | 0.85 | SLC6A4 (0.61) | OPRM1OPRK1OPRD1SLC6A3SLC6A2 | |
| SCHEMBL11260608 | 0.85 | OPRM1 (0.50) | OPRM1OPRK1OPRD1SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150135-A | ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-17 | — | — | US | disclosed |