Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535902 | 0.91 | GPR35 (0.68) | GPR35GAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL688886 | 0.87 | GPR35 (0.62) | GPR35GAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11455527 | 0.85 | GPR35 (0.68) | GPR35GAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL689045 | 0.85 | GPR35 (0.59) | GPR35GAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11453402 | 0.84 | GPR35 (0.58) | GPR35GAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11445340 | 0.84 | GPR35 (0.58) | GPR35GAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11444985 | 0.83 | GPR35 (0.57) | GPR35GAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11446019 | 0.83 | GPR35 (0.57) | GPR35GAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11445190 | 0.81 | GPR35 (0.54) | GPR35GAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11445171 | 0.81 | GPR35 (0.54) | GPR35GAAALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137325-A | Antisecretory oxamic acid esters | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |