Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540161 | 0.90 | MAPT (0.41) | MAPTLMNAHSP90AA1KMT2AMEN1 | |
| SCHEMBL11532987 | 0.89 | KMT2A (0.36) | MAPTLMNAHSP90AA1KMT2AMEN1 | |
| SCHEMBL11532813 | 0.83 | TSHR (0.44) | MAPTLMNAHSP90AA1KMT2AMEN1 | |
| SCHEMBL11531549 | 0.83 | CYP19A1 (0.41) | MAPTLMNAHSP90AA1KMT2AMEN1 | |
| SCHEMBL11536409 | 0.82 | LMNA (0.41) | MAPTLMNAHSP90AA1KMT2AMEN1 | |
| SCHEMBL11534615 | 0.80 | LMNA (0.42) | MAPTLMNAHSP90AA1KMT2AMEN1 | |
| SCHEMBL11534368 | 0.77 | LMNA (0.45) | MAPTLMNAHSP90AA1KMT2AMEN1 | |
| SCHEMBL11531851 | 0.75 | HSP90AA1 (0.35) | MAPTLMNAHSP90AA1KMT2AMEN1 | |
| SCHEMBL11531767 | 0.74 | LMNA (0.45) | MAPTLMNAHSP90AA1KMT2AMEN1 | |
| SCHEMBL11532671 | 0.73 | LMNA (0.35) | MAPTLMNAHSP90AA1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |