SCHEMBL11538337

SCHEMBL11538337

CN(C(=O)n1ccnc1)c1ccc(Cl)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FSCN1 Q16658 1/20 0.54
AHR P35869 1/20 0.46
MAPT P10636 2/20 0.46
GPBAR1 Q8TDU6 2/20 0.41
LMNA P02545 2/20 0.41
ADRA2C P18825 1/20 0.39
IDO1 P14902 2/20 0.38
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3955052 0.87 AHR (0.40) FSCN1AHRMAPTGPBAR1IDO1
SCHEMBL11542419 0.84 AHR (0.50) FSCN1AHRMAPTLMNAADRA2C
SCHEMBL11540763 0.82 AHR (0.56) FSCN1AHRMAPTLMNAADRA2C
SCHEMBL11540399 0.79 AHR (0.51) FSCN1AHRMAPTLMNAADRA2C
SCHEMBL11541542 0.79 MAPT (0.45) AHRMAPTLMNAADRA2CIDO1
SCHEMBL11539808 0.77 CYP19A1 (0.44) AHRMAPTIDO1
SCHEMBL11520464 0.74 CYP19A1 (0.45) AHRMAPTLMNAADRA2CIDO1
Hydrochloric Acid SCHEMBL11394417 0.73 CYP19A1 (0.44) AHRMAPTLMNAADRA2CIDO1
Hydrochloric Acid SCHEMBL11393421 0.73 CYP19A1 (0.44) AHRMAPTLMNAADRA2CIDO1
SCHEMBL11540118 0.72 AHR (0.46) AHRMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154945-A Fungicidal substituted imidazoles THE BOOTS COMPANY LIMITED (GB) 1979-05-15 US disclosed
US-4080462-A Fungicidal compositions containing substituted imidazoles THE BOOTS COMPANY LIMITED (EN) 1978-03-21 US disclosed