SCHEMBL11538499

SCHEMBL11538499

C#CCCNC(=NC#N)SC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11542504 0.90 ALDH1A1 (0.33) ALDH1A1KDM4E
SCHEMBL10718865 0.83 ALDH1A1 (0.37) ALDH1A1KDM4E
SCHEMBL11304952 0.79 ALDH1A1 (0.37) ALDH1A1KDM4E
SCHEMBL19287284 0.79 MCL1 (0.38) ALDH1A1KDM4E
SCHEMBL11219200 0.78 ALDH1A1 (0.36) ALDH1A1KDM4E
SCHEMBL11478217 0.76 GRIN2D (0.35) ALDH1A1KDM4E
SCHEMBL3757247 0.75 KDM4E (0.35) ALDH1A1KDM4E
SCHEMBL10890360 0.75 CA1 (0.36) ALDH1A1KDM4E
SCHEMBL9262677 0.75 EPHX1 (0.38) ALDH1A1
SCHEMBL3760053 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4157340-A N,N'-[Bis(N-cyanoguanyl)]cystamine derivatives BRISTOL-MEYERS COMPANY (US) 1979-06-05 US disclosed