Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537228 | 0.89 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11537232 | 0.89 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11540386 | 0.82 | KDM4E (0.40) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11540389 | 0.82 | KDM4E (0.40) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11541129 | 0.81 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11541126 | 0.81 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11539087 | 0.79 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11539089 | 0.79 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11539361 | 0.79 | PTGES2 (0.38) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11539364 | 0.79 | PTGES2 (0.38) | KDM4ETDP1PKMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136180-A | HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4062960-A | Hypolipidemic alkenesulfonamides | PFIZER INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | disclosed |