Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532830 | 0.92 | LMNA (0.50) | CYP19A1LMNATSHRMAPTKMT2A | |
| SCHEMBL11534596 | 0.91 | CYP19A1 (0.55) | CYP19A1LMNATSHRMAPTRORC | |
| SCHEMBL11532532 | 0.89 | TSHR (0.53) | CYP19A1LMNATSHRRORCKMT2A | |
| SCHEMBL11535387 | 0.88 | LMNA (0.44) | CYP19A1LMNATSHRMAPTKMT2A | |
| SCHEMBL11539190 | 0.87 | TSHR (0.54) | CYP19A1LMNATSHRMAPTKMT2A | |
| SCHEMBL11533025 | 0.87 | CYP19A1 (0.46) | CYP19A1LMNAKCNN4MAPTRORC | |
| SCHEMBL11534023 | 0.86 | CYP19A1 (0.46) | CYP19A1LMNAKCNN4MAPTRORC | |
| SCHEMBL11531974 | 0.85 | CYP19A1 (0.42) | CYP19A1LMNATSHRMAPTKMT2A | |
| SCHEMBL11538888 | 0.85 | MAPT (0.47) | CYP19A1LMNATSHRMAPTKMT2A | |
| SCHEMBL11531173 | 0.85 | TSHR (0.46) | CYP19A1LMNATSHRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |