⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621942 | 0.84 | FFAR4 (0.31) | — | |
| SCHEMBL11533653 | 0.84 | FFAR4 (0.31) | — | |
| SCHEMBL11622876 | 0.80 | — | — | |
| SCHEMBL536475 | 0.72 | GPR84 (0.31) | — | |
| SCHEMBL315847 | 0.70 | FFAR4 (0.31) | — | |
| SCHEMBL76391 | 0.69 | GPR84 (0.37) | — | |
| SCHEMBL35143 | 0.69 | GAA (0.38) | — | |
| SCHEMBL9577728 | 0.69 | GAA (0.38) | — | |
| SCHEMBL431527 | 0.69 | GAA (0.38) | — | |
| SCHEMBL434149 | 0.69 | GAA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |