Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423470 | 0.82 | AHR (0.52) | AHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL9423648 | 0.82 | MEN1 (0.56) | AHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL30738449 | 0.82 | MEN1 (0.56) | AHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL11536604 | 0.80 | AHR (0.50) | AHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL11536163 | 0.80 | AHR (0.53) | AHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL17787304 | 0.80 | MEN1 (0.58) | AHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL11534689 | 0.80 | AHR (0.50) | AHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL11539885 | 0.80 | AHR (0.53) | AHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL11537513 | 0.78 | NQO1 (0.54) | AHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL9423782 | 0.77 | AHR (0.48) | AHRMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147806-A | Anti-inflammatory and analgesic medicaments | LABORATOIRES CREAT (FR) | 1979-04-03 | — | — | US | claimed |
| US-4147806-A | Anti-inflammatory and analgesic medicaments | LABORATOIRES CREAT (FR) | 1979-04-03 | — | — | US | disclosed |