Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539885 | 0.87 | AHR (0.53) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL9423470 | 0.86 | AHR (0.52) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL30738449 | 0.86 | MEN1 (0.56) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL9423648 | 0.86 | MEN1 (0.56) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11536604 | 0.83 | AHR (0.50) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11536163 | 0.83 | AHR (0.53) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11534689 | 0.83 | AHR (0.50) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11539377 | 0.83 | MEN1 (0.45) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11536829 | 0.83 | MEN1 (0.45) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11537513 | 0.81 | NQO1 (0.54) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130331413-A1 | DEFENSIN-LIKE MOLECULES AS NOVEL ANTIMICROBIAL AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-12-12 | — | — | US | claimed |
| US-9351963-B2 | Defensin-like molecules as novel antimicrobial agents | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2016-05-31 | — | — | US | disclosed |
| US-9351963-B2 | Defensin-like molecules as novel antimicrobial agents | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2016-05-31 | — | — | US | disclosed |
| US-9351963-B2 | Defensin-like molecules as novel antimicrobial agents | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2016-05-31 | — | — | US | disclosed |
| US-20130331413-A1 | DEFENSIN-LIKE MOLECULES AS NOVEL ANTIMICROBIAL AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130331413-A1 | DEFENSIN-LIKE MOLECULES AS NOVEL ANTIMICROBIAL AGENTS | DBNL, DNASE1L3, STING1 | MEN1 3766/4885KMT2A 4781/4885MAPT 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.