Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863692 | 0.82 | MAPT (0.44) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL11883060 | 0.82 | MAPT (0.44) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL30428269 | 0.81 | — | — | |
| SCHEMBL17071965 | 0.81 | — | — | |
| SCHEMBL9366064 | 0.78 | MAPT (0.37) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL13646328 | 0.78 | CA1 (0.35) | CA1CA2KDM4E | |
| SCHEMBL2760377 | 0.77 | MAPT (0.39) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL4544647 | 0.76 | MAPT (0.32) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL17538638 | 0.76 | MAPT (0.32) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL11283293 | 0.76 | MAPT (0.32) | MAPTCA12GMNNALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52000250-A | — | — | None | — | — | JP | disclosed |
| US-4133840-A | Preparation of 4-homoisotwistane, (tricyclo[5.3.1.03,8 ]undecane) | KAO SOAP CO., LTD. (JP) | 1979-01-09 | — | — | US | disclosed |
| US-4086285-A | Tricyclo[6.2.1.02,6 ]undeca-2(6)-ene and process for hydride transfer reduction rearrangement of same | KAO SOAP CO., LTD. (JA) | 1978-04-25 | — | — | US | disclosed |
| JP-S52250-A | PROCESS FOR PREPARATION OF 8-EXO-HYDROXY-ENDO-TRICYCLO-(5,2,2,02,6) ) UNDE CANE | KAO CORP | 1977-01-05 | — | — | JP | disclosed |